1、蛋白质合成生物技术。围绕功能蛋白质（蛋白材料、生物酶、食品蛋白、医药蛋白等），利用合成生物学和机器学习技术设计、进化功能蛋白分子，开发蛋白质高效合成工艺；

2、细胞工厂创建与发酵优化。围绕功能小分子（子囊霉素、雷帕霉素、稀有人参皂苷、麦角硫因、戊二胺等），利用基因编辑、代谢调控和系统分析，实现细胞工厂的智能设计和高效运行。

本科生课程：《微生物学》；《微生物学实验》；《材料合成生物学》；《生产实习》；

研究生课程：《生命科学与生物技术》

Biomolecules期刊客座编辑

以第一/通讯作者发表SCI论文（Engineering、CEJ、B&B、ACS Sus Chem. Eng、CC、CES等）40余篇，授权/申请发明专利10余项。

入选“北洋学者•青年骨干教师计划”、获沈志康奖教金等。

天津大学优秀本科生毕业设计指导教师，天津大学优秀硕士论文指导教师。

主持国家重点研发项目子课题、国家自然科学基金、天津市自然科学基金、企业委托项目、天津大学自主基金等多项课题。

[1]. Haishan Qi#, Yihang Gao#, Lin Zhang, Zhongxin Cui, Xiaojie Sui, Jianfan Ma, Jing Yang, Zhiquan Shu, and Lei Zhang*. Rational design and mechanism insight of an efficient antifreeze peptide for cryopreservation. Engineering, 2024, 34: 164-173.

[2]. Wang Y, Tian G, Huang J, Wu W, Cui Z, Lei Zhang*, Haishan Qi*, Mussel-inspired protein-based nanoparticles for curcumin encapsulation and promoting antitumor efficiency. International Journal of Biological Macromolecules, 2024: 132965.

[3]. Meirong Zhao, Jianfan Ma, Lei Zhang, Haishan Qi*, Engineering strategies for enhanced heterogenous protein production by Saccharomyces cerevisiae, Microbial cell factories, 2024, 23(1): 32.

[4]. Xiang Lan, Meirong Zhao, Xiangyu Zhang, Hao Zhang, Lei Zhang*, Haishan Qi*. Mussel-inspired proteins functionalize catheter with antifouling and antibacterial properties, International Journal of Biological Macromolecules, 2023, 245: 125468.

[5]. Lan X#, Zhang H#, Qi, HS*, Liu SM, Zhang XY, Zhang, L*. Custom-design of triblock protein as versatile antibacterial and biocompatible coating. Chemical Engineering Journal, 2023, 454: 140185.

[6]. Zhihua Li#, Xue Zhang#, Haishan Qi*, Xiaowei Huang*, Jiyong Shi, Xiaobo Zou*. A novel renewable electrochemical biosensor based on mussel-inspired adhesive protein for the detection of Escherichia coli O157:H7 in food. Sensors and Actuators B: Chemical, 2022,372, 132601.

[7]. Du, Y., Pu, Z., Kang, H., Mi, J., Liu, S., Qi, H*, & Zhang, L. Zwitterionic Peptides Encircling-assisted Enhanced Catalytic Performance of Lysine Decarboxylase for Cadaverine Biotransformation and Mechanism Analyses. Chemical Engineering Science, 2022,251,117447.

[8]. Zheng WW, Liu M, Qi HS*, Zhang C, Liu SM, Zhou X, Zhang L, Fan DD, Mussel-inspired Triblock Functional Protein Coating with Endothelial Cell Selectivity for Endothelialization. Journal of Colloid and Interface Science, 2020, 576, 68-78.

[9]. Qi HS, Zhang C, Guo HS, Zheng WW, Yang J, Zhou X, Zhang L, Bioinspired Multifunctional Protein Coating for Antifogging, Self-Cleaning, and Antimicrobial Properties. ACS Applied Materials & Interfaces, 2019, 11, 24504-24511.

[10]. Qi HS, Zheng WW, Zhou X, Zhang C, Zhang L*, Mussel-inspired chimeric protein as a novel facile antifouling coating. Chemical Communications, 2018, 54, 11328-11331.