1. 基于人工智能的结晶过程分析技术（PAT）与过程控制

2. 药物结晶过程连续化与过程强化

3. 超纯熔融结晶

4. 结晶过程仪器与装备开发

1. 博士研究生课程《现代颗粒科学与晶体形态学》

2. 硕士研究生课程《工业结晶与粒子过程》

3. 留学生课程《Computer Simulation of Chemical Processes》

期刊Crystals 客座编辑；期刊 Industrial & Engineering Chemistry Research、Cystal Growth and Design、CrystEngComm、 Chemical Engineering Research and Design 、Journal of Crystal Growth、Journal Molecular Liquid、Crystal 等期刊审稿人。

2021年 “头孢类晶型药物绿色合成和高效精制的关键共性技术与产业化“ 获得 河北省医药行业科学技术进步奖，一等奖，20210304-6 （6/17）

1. 山东省重点研发计划（重大科技创新工程），2021CXGC010514，高端原料药精准微粉化共性关键技术创新、制剂产业化及一致评价研究，2021.10-2024.12, 天津大学子课题 173.55万，主持；

2. 国家自然科学基金面上项目，22378296；药物结晶及其二次过程的智能谱图软测量和模型预测控制；2024年01月至 2027年 12月，主持；

3. 国家自然科学基金委员会青年科学基金，22008173，基于图像+AI技术的溶液结晶原位显微监测与过程数据挖掘，2021.01-2023.12

1. Tuo Yao, Jian Liu, Xuxing Wan, Beibei Li, Sohrab Rohani, Zhenguo Gao*, Junbo Gong, Deep-learning based in-situ image monitoring crystal polymorph and size distribution: modeling and validation, AIChE J, 2023, e18279;

2. Shengzhe Jia, Liu yang Yu, Zhenguo Gao*, Songgu Wu, Weiwei Tang*, Jingkang Wang, Junbo Gong, Performance and analysis of key factors on the design of melt crystallization‐based separation process. AIChE J, 2023, 18117；

3. Jian Liu, Qingyang Zhang, Mingyang Chen, Zhenguo Gao*, Sohrab Rohani, Junbo Gong, A verified open-access AI-based chemical microparticle image database for in-situ particle visualization and quantification in multi-phase flow. Chemical Engineering Journal, 451, (2023): 138940；

4. Tiantian Tao, Zhenguo Gao*, Chen Fang, Jiayin Zhang, Jun Xu, Huaiyu Yang, Junbo Gong Enhancement of protein crystallization with the application of Taylor vortex and Poly (ionic liquid) s. Chemical Engineering Science, 252, (2022): 117501;

5. Zhenguo Gao, Sohrab Rohani, Junbo Gong, Jingkang Wang. Recent developments in the crystallization process: toward the pharmaceutical industry. Engineering, 3, 3, 2017, 343-353;

6. Zhenguo Gao, Yuanyi Wu, Ying Bao, Junbo Gong, Jingkang Wang, and Sohrab Rohani. Image Analysis for In-Line Measurement of Multi-Dimensional Size, Shape and Polymorphic Transformation of L-glutamic Acid Using Deep. Crystal Growth & Design, 18, 8, 2018, 4275-4281.